The Author


Jessica R Oesterheld, M.D. is the Medical Director of the Spurwink School in Portland Maine. She was previously the Director of Training, Division of Child and Adolescent Psychiatry, University of South Dakota School of Medicine Sioux Falls, South Dakota.

She a graduate of Mount Holyoke College and Tufts Medical School and completed residencies in General, College and Child and Adolescent Psychiatry.

She has been a cytochrome maven since 1992. Her interest arose from clinical experiences with patients with side effects based on CYP-based drug interactions. She has authored the following papers or chapters that review cytochromes and their development and interactions.

Oesterheld JR, UGTs for Clinicians in Psychosomatics (in press, Spring 2002)
Oesterheld JR and Flockhart DA : Hepatic P450 Cytochromes-Based Drug Interactions in: Textbook of Child and Adolescent Psychiatry. Oxford University Press (in press, Fall 2002)
Oesterheld JR, Parmalee D, Shader RI: Child Psychiatry in Manual of Psychiatric Therapeutics (in press, Spring 2002)
Martin A, Oesterheld J et al: Basic Psychopharmacology in Lewis' Textbook of Child Psychiatry, third edition (in press, Fall 2002)
Oesterheld JR and Martin A: Child and Adolescent Psychopharmacology in Curriculum for Teaching Psychiatric Residents: American Society of Clinical Pharmacology, 2001
Oesterheld JR: Oral contraceptives in: The Cytochromes P450 System Cozza and Armstrong (eds) American Psychiatric Association Press , Washington, 2001
Shader RI and Oesterheld JR: (editorial):Contraceptive Effectiveness: cytochromes and induction: J Clin Psychopharmacol 20:119-121, April 2000
Flockhart D, Oesterheld JR: P450 cytochromes and Drug Interactions. Child and Adolesc Psychiatric Clinics of North America 9:43-76, 2000
Oesterheld JR, Osser DA: Obsessive Compulsive Disorder: CYP-based drug interactions. Journal of Practical Psychiatry and Behavioral Health 5:179-183, May 1999
Oesterheld JR: A Review of Developmental Aspects of Cytochrome P450. J Child Adolesc Psychopharmacol 8: 8:161-174, 1998
Oesterheld, JR and Shader RI: Cytochromes: A Primer for Child Psychiatrists, J Am Acad Child Adolesc Psychiatry 37:447-450, April 1998
Oesterheld, JR and Kallapelli R: Clomipramine and grapefruit juice: changing the metabolitic ratio. (letter to editor) J Clin Psychopharmacol 17:62-63 February 1997
Oesterheld JR : Erythromycin and Clomipramine: noncompetitive inhibition of demethylation (letter to editor) J Child Adolescent Psychopharmacol 6:211-12, November 1996
Oesterheld JR: TCA cardiotoxicity: the latest (letter to the editor) J of Am Acad Child Adolesc Psychiatry 35:701-702, June 1996

[biography updated 12/18/01]