The P450 and P-glycoprotein Drug Interactions

Web Sites

Compiled by

Jessica Oesterheld, M. D.

David N. Osser, M.D.

Updated 13 July 2003

Cytochromes (P450)

P450 drug interactions software www.mhc.com/Cytochromes/
CYP Allelic Nomenclature committee www.imm.ki.se/CYPalleles/
CYP Sequences drnelson.utmem.edu/CytochromeP450.html
General Source for links to other CYP Web pages www.icgeb.trieste.it/p450/
CYP charts http://medicine.iupui.edu/flockhart
Comprehensive CYP metabolism lists www.gentest.com/human_p450_database/srchh450.asp
www.edhayes.com/startp450.html
AIDs drug interactions

• http://www.hiv-druginteractions.org/
• www.hopkins-aids.edu/geneva/hilites_flex_drug.html
• www.hivatis.org/druginteractions.html
• http://www.edhayes.com/startp450.html

FDA Medwatch www.fda.gov/medwatch/safety.htm

Abstracts from the most recent 30 days for "CYP metabolism" from PubMed www.issx.org/p450pg.htm
Course on Clinical Pharmacology with several lectures on CYPs, genetics and drug interactions www.cc.nih.gov/ccc/principles/

Outstanding Articles

• An review with many tables www.anaesthetist.com/physiol/basics/metabol/cyp/cyp.htm
• A general article on drug metabolism that includes CYPs www.uspharmacist.com/newlook/ce/bioavail/lesson.cfm
• Drug interactions of antidepressants in the elderly www.postgradmed.com/issues/1999/11_99/cadieux.htm
• A clinical article on CYP3As www.uspharmacist.com/NewLook/DisplayArticle.cfm?item_num=20
• A review article on clinical aspects of P450s www.aafp.org/afp/980101ap/cupp.html
• A general article on drug interactions and CYPs www.postgradmed.com/issues/1999/02_99/johnson.htm
• Images of P450s; and P450 in relation to the brain and cocaine home.earthlink.net/~cpardee/cellandmembrane.html
• Drug interactions of newer atypical antipsychotics www.mmhc.com/hhcc/articles/HHCC9810/lam.html

P-glycoproteins (PGP)

Discussion and interactions table www.mhc.com/PGP/
PGPs in AIDS - discussion and interactions table www.aidsinfonyc.org/tag/science/pgp.html
Website for P-glycoprotein nomenclature http://nutrigene.4t.com/humanabc.htm

http://nutrigene.4t.com/humanabc.htm

Drug Absorption / Metabolism

Abstracts from the most recent 30 days for "drug absorbtion" from PubMed http://www.issx.org/abspg.htm
Abstracts from the most recent 30 days for "Conjugation" from PubMed http://www.issx.org/conjpg.htm

To Mental Health Connections Cytochromes home page.