The following describes an algorithm-oriented psychopharmacology course for residents in psychiatry.
Oct. 15, 2003 Introduction: Goals, Methods, Requirements of the Course.
Evidence-Based Medicine. How to Critique the Evidence
Lecture by Drs. Osser and Levitt
Readings: Osser DN et al. Algorithms, guidelines, and evidence-based psychopharmacology training for psychiatry residents. Submitted to Academic Psychiatry 2003 AND Miser WF. Critical appraisal of the literature: how to assess an article and still enjoy life. In: Evidence-based clinical practice: concepts and approaches. Geymann JP, Deyo RA, Ramsey SD, eds. Boston, Butterworth-Heinemann, 2000:41-56.
Oct. 22 Schizophrenia I Case Conference
Oct. 29 Schizophrenia I Clinical Paper
Neuroscience Paper
Reading: Osser DN, Sigadel RD. Short-term inpatient pharmacotherapy of schizophrenia. Harvard Review of Psychiatry 2001;9:89-104.
Nov. 5 Harvard Education Day at McLean
Nov. 12 Schizophrenia II Case Conference
Nov. 19 Schizophrenia II Clinical Paper
Neuroscience Paper
Reading: Kane JM et al. Long-acting injectable risperidone: efficacy and safety of the first long-acting atypical antipsychotic. Am J Psychiatry 2003;160(6):1125-1132.
Nov. 26 Depression I Case Conference
Dec. 3 Depression I Algorithm Review – led by the faculty
Neuroscience Paper
Reading: Osser DN. Flowchart for the Algorithm for the Pharmacotherapy of Depression. From mhc.com/Algorithms, the Psychopharmacology Algorithm Project at the Harvard South Shore Residency Training Program. 2003
Dec. 10 Bipolar Depression Case Conference .
Dec. 17 Bipolar Depression Clinical Paper
Neuroscience Paper
Reading: Dantzler A, Osser DN. Algorithms for the pharmacotherapy of acute depression in patients with bipolar disorder. Psychiatric Annals 1999;29:270-284.
Dec. 24 No Meeting (Christmas)
Dec. 31 No Meeting (New Years)
Jan. 7, 2004 Bipolar Mania Case Conference
Jan. 14 Bipolar Mania Clinical Paper
Neuroscience Paper
Reading: Suppes T et al. Texas Medication Algorithm Project, Phase 3: Clinical results for patients with a history of mania. J Clin Psychiatry 2003;64(4):370-382.
Jan. 21 Anxiety Disorders I Case Conference
Jan. 28 Anxiety Disorders I Algorithm Review - led by the faculty
Neuroscience Paper
Reading: Osser DN et al Algorithms for the pharmacotherapy of anxiety disorders in patients with chemical abuse and dependence. Psychiatric Annals 1999;29:285-300 AND Osser DN et al.. Flowchart for the Algorithm for the Pharmacotherapy of Depression. From mhc.com/Algorithms, the Psychopharmacology Algorithm Project at the Harvard South Shore Residency Training Program. 2003 update.
Feb. 4 Anxiety Disorders II - PTSD Case Conference
Feb. 11 Anxiety Disorders II - PTSD Clinical Paper
Neuroscience Paper
Reading: Hamner MB et al. Quetiapine treatment in patients with PTSD: an open trial of adjunctive therapy. J Clin Psychopharmacology 2003:23(1):15-20 AND Stein MB et al. Adjunctive olanzapine for SSRI-resistant combat-related PTSD: a double-blind, placebo-controlled study. Am J Psychiatry 2002;159:1777-1779.
Feb. 18 Anxiety Disorders III - Case Conference
Feb. 25 Anxiety Disorders III - Clinical Paper
Neuroscience Paper
Reading: Bruce SE et al. Are benzodiazepines still the medication of choice
for patients with panic disorder with or without agoraphobia? Am J Psychiatry
2003;160(8):1432-1438.
March 3 Schizophrenia/Schizoaffective Disorder Revisited -
Case Conference
March 10 Schizophrenia/Schizoaffective Disorder Revisited -
Algorithm Review – led by the faculty
Neuroscience Paper
Reading: Osser DN. Flowchart for the Consultant for the Pharmacotherapy of Schizophrenia. From mhc.com/Algorithms, the Psychopharmacology Algorithm Project at the Harvard South Shore Residency Training Program. 2003 update.
March 17 Harvard Research Day/Mysell Lecture
March 24 Personality Disorders - Case Conference
March 31 Personality Disorders Clinical Paper
Neuroscience Paper
Reading: APA Practice Guidelines for Patients with Borderline Personality Disorder. Am J Psychiatry 2001;158(10, supplement):1-47. Focus on the summary of recommendations (pg 4-6) and the review of pharmacotherapy evidence and algorithms, pg 35-43)
April 7 Substance Abuse I - Case Conference
April 14 Substance Abuse I Clinical Paper
Neuroscience Paper
Reading: Le Bon O et al. Double-blind, placebo-controlled study of the efficacy of trazodone in alcohol post-withdrawal syndrome: polysomnographic and clinical evaluations. J Clin Psychopharmacol 2003;23(4):377-383. AND Kranzler HR et al. Targeted naltrexone for early problem drinkers. J Clin Psychopharmacol 2003;23(3):294-304.
April 21 Substance Abuse II Case Conference
April 28 Substance Abuse II Clinical Paper
Neuroscience Paper
Reading: Fudala PJ et al. Office-based treatment of opiate addiction with
a sublingual tablet formulation of buprenorphine and naloxone. NEJM 2003;349:949-58.
May 5 No Meeting (APA)
May 12 Bipolar Disorder III Case Conference
May 19 Attention Deficit Hyperactivity Disorder Case Conference
May 26 Retreat (Date subject to change: if so, shift agenda to this date)
June 2 ADHD Clinical Paper
Neuroscience Paper
Readings: Michelson D et al. Atomoxetine in the treatment of children and
adolescents with ADHD: a randomized, placebo-controlled, dose-response study.
Pediatrics 2001;108(5):1-9
June 9. Update: New Research Abstracts from APA –
Psychopharmacology
Lecture by Drs. Osser and Levitt
June 16 Update: New Research Abstracts from APA –
Psychopharmacology and Neuroscience
Lecture by Drs. Osser and Levitt
June 23 Feedback Session