The following describes an algorithm-oriented psychopharmacology course for residents in psychiatry.
Year 1: 2001-2002
Oct. 24, 2001 Introduction. Goals, Methods, Requirements of the Course.
Evidence-Based Medicine. How to Critique the Evidence
Dr. Osser
Oct. 31 Schizophrenia I Case Conference Dr. Ceranoglu
Nov. 7 Schizophrenia I Algorithm Paper and Resident-Selected Paper
Drs. Sassani and Ceranoglu
Nov. 14 Schizophrenia II Case Conference Dr. Weigle
Nov. 21 Schizophrenia II Algorithm Paper and Resident-Selected Paper
Drs. Borek and Weigle
Nov. 28 Depression I Case Conference Dr. Babbage
Dec. 5 Depression I Algorithm Paper and Resident-Selected Paper
Drs. Darabus and Babbage
Dec. 12 Depression II Case Conference Dr. Savu
Dec. 19 Depression II Algorithm Paper and Resident-Selected Paper
Drs. Weigle and Savu
Dec. 26 No Meeting (Christmas)
Jan. 2, 2002 Bipolar Depression Case Conference Dr. Badgaiyan
Jan. 9 Bipolar Depression Algorithm Paper and Resident-Selected Paper
Drs. Babbage and Badgaiyan
Jan. 16 Bipolar Mania Case Conference Dr. Borek
Jan. 23 Bipolar Mania Algorithm Paper and Resident-Selected Paper
Drs. Savu and Borek
Jan. 30 Panic Disorder Case Conference Dr. Sebastian
Feb. 6 Panic Disorder Algorithm Paper and Resident-Selected Paper
Drs. Badgaiyan and Sebastian
Feb. 13 Posttraumatic Stress Disorder Case Conference Dr. Radisic
Feb. 20 PTSD Algorithm Paper and Resident-Selected Paper
Drs. Martija and Radisic
Feb. 27 Social Anxiety Disorder & Generalized Anxiety Disorder Case
Conference Dr. Akhter
March 6 SAD and GAD Algorithm Paper and Resident-Selected Paper
Drs. Ceranoglu and Akhter
March 13 Harvard Education Day
March 20 Obsessive-Compulsive Disorder Case Conference Dr. Darabus
March 27 OCD Algorithm Paper and Resident-Selected Paper
Drs. Sebastian and Darabus
April 3 Dementia Case Conference Dr. Rivera
April 10 Dementia Algorithm Paper and Resident-Selected Paper
Drs. Radisic and Rivera
April 17 Eating Disorders Case Conference Dr. Kittay
April 24 Eating Disorders Algorithm Paper and Resident-Selected Paper
Drs. Akhter and Kittay
May 1 The Alcoholic Patient Case Conference Dr. Martija
May 8 The Alcoholic Patient Papers
Drs. Rivera and Martija
May 15 Attention Deficit Hyperactivity Disorder Case Conference
Dr. Emanuel Frank
May 22 No Meeting (APA)
May 29 Retreat (Date subject to change: if so, shift agenda to this date)
June 5 ADHD Algorithm Paper and Resident-Selected Paper
Drs. Kittay and Frank
June 12 Child and Adolescent Psychopharmacology Papers
Dr. Sassani
June 19 Update: Important New Research Abstracts from APA
Dr. Osser
June 26 Open Date
Year 2: 2002-2003
Sept. 25, 2002 Introduction: Goals, Methods, Requirements of the Course.
Evidence-Based Medicine I. How to Critique the Evidence
Dr. Osser
Readings: Miser WF. Critical appraisal of the literature: how to assess an article and still enjoy life. In: Evidence-based clinical practice: concepts and approaches. Geymann JP, Deyo RA, Ramsey SD, eds. Boston, Butterworth-Heinemann, 2000:41-56. AND Geddes J. Glossary of Terms in EBM. In: Clinical Evidence Mental Health. BMJ Publishing Group, London, England, 2002:ix-xii.
Oct. 2 Prite Examination
Oct. 9 Prite Examination
Oct. 16 Schizophrenia I Case Conference Dr. Dolliver
Oct. 23 Schizophrenia I Case Conference Paper Dr. Dolliver
Syllabus Paper Dr. Akhter
Reading: Conley RR, Mahmoud R. A randomized double-blind study of risperidone and olanzapine in the treatment of schizophrenia or schizoaffective disorder. Am J Psychiatry 2001;158:765-774. AND Osser DN. Should polypharmacy be routine in patients with schizophrenia? J Psychotic Disorders Rev and Commentaries 2002;6(3):in press.
Oct. 30 Schizophrenia II Case Conference Dr. Shao
Nov. 6 Schizophrenia II Case Conference Paper Dr. Shao
Syllabus Paper Dr. Ceranoglu
Reading: Volavka J et al. Clozapine, olanzapine, risperidone, and haloperidol in the treatment of patients with chronic schizophrenia and schizoaffective disorder. Am J Psychiatry 2002;159:255-262.
Nov. 13 Harvard Education Day at McLean
Nov. 20 Depression I Case Conference Dr. Ahmad
Nov. 27 Depression I Case Conference Paper Dr. Ahmad
Syllabus Paper Dr. Kittay
Reading: Fava M et al. Double-blind study of high-dose fluoxetine versus lithium
or desipramine augmentation of fluoxetine in partial responders and non-responders
to fluoxetine. J Clin Psychopharmacol 2002;22:379-387.
Dec. 4 Depression II Case Conference Dr. DeSilva
Dec. 11 Depression II Case Conference Paper Dr. DeSilva
Syllabus Paper Dr. Radisic
Reading: Glassman AH. Sertraline treatment of major depression in patients
with acute MI or unstable angina. JAMA 2002;288:701-709 (Aug. 14)
Dec. 18 Bipolar Depression Case Conference Dr. Saxena
Dec. 25 No Meeting (Christmas)
Jan. 1, 2003 No Meeting (New Year’s)
Jan. 8 Bipolar Depression Case Conference Paper Dr. Saxena
Syllabus Paper Dr. Rivera
Reading: Vieta E et al. A randomized trial comparing paroxetine and venlafaxine in the treatment of bipolar depressed patients taking mood stabilizers. J Clin Psychiatry 2002;63:508-512
Jan. 15 Bipolar Mania Case Conference Dr. Frank
Jan. 22 Bipolar Mania Case Conference Paper Dr. Frank
Syllabus Paper Dr. Sanchez
Reading: Tohen M et al. Efficacy of olanzapine in combination with valproate
or lithium in the treatment of mania in patients partially non-responsive to
valproate or lithium monotherapy. Arch Gen Psychiatry 2002;59:62-29 AND Miller
DS et al. Comparative efficacy of typical and atypical antipsychotics as add-on
therapy to mood stabilizers in the treatment of acute mania. J Clin Psychiatry
2001;62:975-980.
Jan. 29 Panic Disorder Case Conference Dr. Baskin
Feb. 5 Panic Disorder Case Conference Paper Dr. Baskin
Syllabus Paper Dr. Sebastian and Dr. Shirzadi
Reading: Uhlenhuth EH. Do antidepressants selectively suppress spontaneous (unexpected) panic attacks? A replication. J Clin Psychopharmacol 2000;20:622-627 AND Simon NM. Hypothyroidism and hyperthyroidism in anxiety disorders revisited: new data and literature review. Journal of Affective Disorders 2002;69:209-217.
Feb. 12 Posttraumatic Stress Disorder Case Conference Dr. Shirzadi
Feb. 19 PTSD Case Conference Paper Dr. Shirzadi
Syllabus Paper Dr. Karakus
Reading: Martenyi F et al. Fluoxetine versus placebo in PTSD. J Clin Psychiatry 2002;63:199-206.
Feb. 26 Social Anxiety Disorder & Generalized Anxiety Disorder Case
Conference Dr. Darabus
March 5 SAD and GAD Case Conference Paper Dr. Darabus
Syllabus Paper Dr. Savu
Reading: Federoff IC, Taylor S. Psychological and pharmacological treatments of social phobia: a meta-analysis. J Clin Psychopharmacol 2001;21:311-324.
March 12 Obsessive-Compulsive Disorder Case Conference Dr. Ceranoglu
March 19 Harvard Research Day/Mysell Lecture, Dr. Ken Wells
March 26 OCD Case Conference Paper Dr. Ceranoglu
Syllabus Paper Dr. Ahmad
Reading: McDougle CJ et al. A double-blind, placebo-controlled study of risperidone addition to SSRI-refractory OCD. Arch Gen Psychiatry 2000;57:794-801.
April 2 Dementia Case Conference Dr. Kittay
April 9 Dementia Case Conference Paper Dr. Kittay
Syllabus Paper Dr. Dolliver
Reading: Pollock BG et al. Comparison of citalopram, perphenazine, and placebo for the acute treatment of psychosis and behavioral disturbances in hospitalized, demented patients. Am J Psychiatry 2002;159:460-465
April 16 Eating Disorders Case Conference Dr. Radisic
April 23 Eating Disorders Case Conference Paper Dr. Radisic
Syllabus Paper Dr. DeSilva
Reading: Kaye WH. Double-blind, placebo-controlled administration of fluoxetine
in patients with restricting and bingeing anorexia nervosa. Biological Psychiatry
2001:49(7):644-652.
April 30 Substance Abuse Case Conference Dr. Rivera
May 7 Substance Abuse Case Conference Paper Dr. Rivera
Syllabus Paper Dr. Frank
Reading: Kristal JH et al. Naltrexone in the treatment of alcohol dependence. NEJM 2001;345(Dec. 13):1734-9
May 15 Attention Deficit Hyperactivity Disorder Case Conference
Dr. Sanchez
May 21 No Meeting (APA)
May 28 Retreat (Date subject to change: if so, shift agenda to this date)
June 4 ADHD Case Conference Paper Dr. Sanchez
Syllabus Paper Dr. Saxena
Readings: Spencer T et al. Efficacy of a mixed amphetamine salts compound
in adults with ADHD. Arch Gen Psychiatry 2001;58(8):775-782
June 11 Child and Adolescent Psychopharmacology Papers
Dr. Sebastian and Dr. Shao
Reading: Hoagwood K et al. Evidence-based practice in child and adolescent
mental health services. Psychiatric Services 2001;52(9):1179-1189 AND Pelham
WE et al. Once a day Concerta methylphenidate vs three-times-daily methylphenidate
in laboratory and natural settings. Pediatrics 2001;107(6):1-15
June 18 Update: Important New Research Abstracts from APA
Dr. Osser
June 25 Open Date