The computer consultant will be relying on the accuracy of the history you have given. Are you sure the patient had a poor response to a Standard Typical Neuroleptic in the presence of parkinsonism (cogwheeling, bradykinesia)? We ask that you be sure because responses not based on observation of the patient's current clinical state are presumed to be a less reliable basis for the subsequent assessment questions and recommendations that will follow.
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¹Subsyndromal Depressive Syndrome, or Depression NOS in DSM-4, is a major public health problem that produces significant functional impairment. See Judd LL. Socioeconomic burden of subsyndromal depressive syndrome and major depression in a sample of the general population. Am J Psychiatry 1996;153:1411-1417.
²Mason BJ, Kocsis JH, Ritvo EC, Cutler RB. A double-blind, placebo-controlled trial of desipramine for primary alcohol dependency stratified in the presence or absence of major depression. JAMA March 13, 1996;275(10):761-767.
³Gelenberg A. Biological Therapies in Psychiatry Newsletter 1996;19(7):25-26.