uestion: Has the patient had a past history of being nonresponsive to an adequate trial of any standard, typical neuroleptic? ("adequate" is defined as eight weeks of no response or a partial response that plateaued at an unsatisfactory level, at a dose that was bioavailable as evidenced by the patient having neuroleptic-induced parkinsonism)

Note: A trial of risperidone that produced parkinsonian side effects could be considered equivalent to a trial of a standard, typical neuroleptic.

• Yes

      The history is quite certain: the patient had a poor response in the past
      to a standard, typical neuroleptic, or to risperidone at a dose that produced 
      parkinsonian side effects.

• No or the history is less than certain