Lists of Psychopharmacology Algorithms

Updated 30 January, 2004

Compiled by David N. Osser, M.D. and Robert D. Patterson, M.D.

If you know of other algorithms which should be added to this list, please tell us.

Algorithms are arranged by diagnosis, and are listed chronologically by date of publication, starting with the most recent. General references and collections of brief algorithms are in separate lists at the end. Due to the rapidly changing nature of psychopharmacology practice, we have only included algorithms published since 1997.

Algorithm quality varies. For a discussion of how to evaluate the quality of algorithms, see Osser DN, Patterson RD. Psychopharmacology algorithms. In: Shader RI, ed. Manual of psychiatric therapeutics, third edition. Boston, Little, Brown and Company, in press.



Psychotic Depression

Bipolar Depression

Bipolar Mania

Panic Disorder

Posttraumatic Stress Disorder

Social Anxiety Disorder (Social Phobia)

Obsessive-Compulsive Disorder

Generalized Anxiety Disorder

Osser DN, Renner JAJr., Bayog R. Algorithms for the pharmacotherapy of anxiety disorders in patients with chemical abuse and dependence. Psychiatric Annals 1999;29(5):285-301. Latest update at

Body Dysmorphic Disorder

Phillips KA. Pharmacotherapy of body dysmorphic disorder: a review of impirical evidence and a proposed treatment algorithm. Psychiatric Clinics of North America Annals of Drug Therapy 2000;7:59-82.

Agitation in the Patient with Dementia

Personality Disorders

Attention Deficit Hyperactivity Disorder in Adults

Bhandary AN, Fernandez F, Gregory RJ, et al. Pharmacotherapy in adults with ADHD. Psychiatric Annals 1997;27(8):545-555.

Tobacco Dependence

The Tobacco Use and Dependence Clinical Practice Guideline Panel. A clinical practice guideline for treating tobacco use and dependence: A US public health service report. JAMA 2000;283(24):3244-3254.

Child and Adolescent Psychopharmacology

Developmental Disabilities: Behavioral Disorders

Mikkelsen EJ, McKenna L. Psychopharmacologic algorithms for adults with developmental disabilities and difficult-to-diagnose behavioral disorders. Psychiatric Ann 1999;29(5):302-314.

General Articles on the Theory and Practice of Constructing Algorithms

Testosterone Treatment in Psychiatry

Other References of Interest on Algorithms/Guidelines