Jessica R Oesterheld, M.D. is the Medical Director of the
Spurwink School in Portland Maine. She was previously the Director of Training,
Division of Child and Adolescent Psychiatry, University of South Dakota School
of Medicine Sioux Falls, South Dakota.
She a graduate of Mount Holyoke College and Tufts Medical School and completed residencies in General, College and Child and Adolescent Psychiatry.
She has been a cytochrome maven since 1992. Her interest arose from clinical experiences with patients with side effects based on CYP-based drug interactions. She has authored the following papers or chapters that review cytochromes and their development and interactions.
Oesterheld JR, UGTs for Clinicians in Psychosomatics (in press,
Spring 2002)
Oesterheld JR and Flockhart DA : Hepatic P450
Cytochromes-Based Drug Interactions in: Textbook of Child and Adolescent
Psychiatry. Oxford University Press (in press, Fall 2002)
Oesterheld JR,
Parmalee D, Shader RI: Child Psychiatry in Manual of Psychiatric Therapeutics
(in press, Spring 2002)
Martin A, Oesterheld J et al: Basic
Psychopharmacology in Lewis' Textbook of Child Psychiatry, third edition (in
press, Fall 2002)
Oesterheld JR and Martin A: Child and Adolescent
Psychopharmacology in Curriculum for Teaching Psychiatric Residents: American
Society of Clinical Pharmacology, 2001
Oesterheld JR: Oral contraceptives
in: The Cytochromes P450 System Cozza and Armstrong (eds) American Psychiatric
Association Press , Washington, 2001
Shader RI and Oesterheld JR:
(editorial):Contraceptive Effectiveness: cytochromes and induction: J Clin
Psychopharmacol 20:119-121, April 2000
Flockhart D, Oesterheld JR: P450
cytochromes and Drug Interactions. Child and Adolesc Psychiatric Clinics of
North America 9:43-76, 2000
Oesterheld JR, Osser DA: Obsessive Compulsive
Disorder: CYP-based drug interactions. Journal of Practical Psychiatry and
Behavioral Health 5:179-183, May 1999
Oesterheld JR: A Review of
Developmental Aspects of Cytochrome P450. J Child Adolesc Psychopharmacol 8:
8:161-174, 1998
Oesterheld, JR and Shader RI: Cytochromes: A Primer for
Child Psychiatrists, J Am Acad Child Adolesc Psychiatry 37:447-450, April 1998
Oesterheld, JR and Kallapelli R: Clomipramine and grapefruit juice:
changing the metabolitic ratio. (letter to editor) J Clin Psychopharmacol
17:62-63 February 1997
Oesterheld JR : Erythromycin and Clomipramine:
noncompetitive inhibition of demethylation (letter to editor) J Child
Adolescent Psychopharmacol 6:211-12, November 1996
Oesterheld JR: TCA
cardiotoxicity: the latest (letter to the editor) J of Am Acad Child Adolesc
Psychiatry 35:701-702, June 1996
[biography updated 12/18/01]
David N. Osser, M.D. is a national, and international consultant in clinical psychopharmacology with over 25 years of experience in a wide variety of settings. He is most well known for the development of systematic, comprehensive algorithmic pathways for evidence-supported psychopharmacological treatment of depressive, psychotic, and anxiety disorders. In collaboration with Robert Patterson, M.D., these algorithms have been produced in an Internet-based "virtual psychopharmacology consultation" interactive computer format. These may be found at the web site www.mhc.com/Algorithms. In October 2001 this web site won a Kanter Foundation Award for "journalists who foster knowledge about the benefits of collecting and standardizing data on health outcomes, so patients and clinicians can use scientific, evidence-based information to guide their treatment decisions."
Dr. Osser is an associate professor of psychiatry at Harvard Medical School. He is an author of more than 50 academic products, including journal articles, software, monographs, book chapters, and abstracts. He received four awards for outstanding teaching, and two Exemplary Psychiatrist awards from the National Alliance for the Mentally Ill (NAMI) and from the Massachusetts chapter of NAMI. He has been on the staff of Taunton State Hospital for over 25 years and currently is Director of the Psychopharmacology Consultation Service and Director of Medical Practice Evaluation and Management. He is also on the staff of the Brockton Department of Veterans Affairs Medical Center, where he is the Psychiatrist for the Domiciliary program for homeless veterans. He is also President of the Massachusetts Psychiatric Society, a district branch of the American Psychiatric Association.
Dr. Osser is a member of the International Psychopharmacology Algorithm Project, directed by Kenneth Jobson, M.D. Under their auspices, he has presented his algorithms and software in Japan and China in the past several years. He has been named an "Honorary International Advisory Member of the Chinese Psychopharmacology Algorithm Project with gratitude from the Beijing University Institute of Psychiatry and the Ministry of Health of the People's Republic of China."
He lives in Needham, Massachusetts with his wife Stephanie, two children, Rosie (19) and Daniel (16), and two turtles, Hypotenuse 4.0 and Hypotenuse 5.0.
[biography updated 1/7/02]